Great literature transcends time because of its inherent qualities: the author has a clear purpose, the author achieves that purpose, and the purpose is a worthwhile one.
"What haunts humanity is its hatred of itself, and it is this 'guilt' which, more than anything else, must be overcome." (Alan Taylor, The University of Texas At Arlington)
What role does guilt play within the context of Death of a Salesman and our lives? Your goal should be to make assertions that broaden other's perception. If you lack wisdom or insight, do some research.